Alexandria Apothecary Archive

Tag: anticoagulant safety

Phenytoin and Warfarin: How They Interact and What You Need to Monitor

Phenytoin and Warfarin: How They Interact and What You Need to Monitor

Dec 15, 2025 / 8 Comments

Phenytoin and warfarin interact in two dangerous phases: an early INR spike from protein displacement, followed by a delayed drop due to enzyme induction. Close monitoring is essential to avoid bleeding or clotting.

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