Besifloxacin: What It Is, How to Use It, and What to Watch For
If you’ve been prescribed Besifloxacin, you’re probably dealing with an eye infection like bacterial conjunctivitis. It’s a fluoroquinolone antibiotic that comes as eye drops, designed to kill the bacteria causing redness, discharge, and irritation. Think of it as a targeted cleaning crew for the surface of your eye.
When and Why Doctors Choose Besifloxacin
Besifloxacin is often the go‑to when a doctor sees an infection that won’t clear up on its own. It works against a broad range of common eye pathogens, including Staphylococcus and Streptococcus species. The drug is approved for both adults and children over two years old, making it a flexible option in many practices.
Because it’s a drop, you get a high concentration right where it’s needed, and you avoid the systemic side effects that oral antibiotics can cause. That’s a big win for people who can’t tolerate pills or have liver/kidney concerns.
How to Take Besifloxacin Properly
First, wash your hands. Then, tilt your head back a bit, pull down the lower eyelid to create a pocket, and squeeze one drop into that pocket. Close your eye gently for about 30 seconds – don’t blink or rub, otherwise the drug can spill out.
Typical dosing is two drops in the affected eye every two hours for the first day, then three times a day for the next two days. Always follow what your doctor wrote on the prescription; timing matters because keeping the drug’s level steady helps kill the bacteria faster.
If you miss a dose, take it as soon as you remember unless it’s almost time for the next scheduled dose. In that case, skip the missed one and continue with your regular schedule. Don’t double‑dose to make up for a forgotten one.
Common Side Effects You Might Feel
Most people tolerate Besifloxacin well. Some report temporary eye stinging, burning, or a mild increase in tearing right after the drop. These sensations usually fade within a few minutes.
Rarely, you could see more serious reactions like swelling of the eyelid, rash, or worsening redness. If any of these happen, stop using the drops and call your healthcare provider right away.
Things to Watch Out for: Interactions & Precautions
Because Besifloxacin stays on the eye surface, it rarely interacts with other medicines. However, if you use other eye drops (like lubricating drops or glaucoma meds), wait at least five minutes between applications to avoid washing one out with the other.
Tell your doctor if you have a history of tendon problems or if you’re taking other fluoroquinolone antibiotics. While eye‑drop exposure is low, a cautious approach is always best.
How to Store and Handle the Medication
Keep the bottle at room temperature, away from direct sunlight and heat. Don’t freeze it. If you notice the solution turning yellow or cloudy, discard it – that means it’s expired or contaminated.
Make sure the tip doesn’t touch your eye, eyelid, or any surface. Contamination can lead to infection or reduced effectiveness.
Quick FAQ
- Can I wear contacts while using Besifloxacin? Remove contacts before applying drops, wait at least 15 minutes, then put them back.
- Is it safe during pregnancy? The eye‑drop route limits systemic exposure, but always check with your OB‑GYN.
- How soon will I feel better? Most patients notice reduced redness and discharge within 24‑48 hours.
Bottom line: Besifloxacin is a convenient, effective eye‑drop antibiotic for bacterial infections. Follow the dosing schedule, keep the bottle clean, and watch for any unusual symptoms. If you stay on top of these steps, you’ll likely see your eyes clear up fast and safely.

Besifloxacin for Children: Safety & Effectiveness in Pediatric Eye Infections
Aug 22, 2025 / 0 Comments
A thorough look at Besifloxacin’s safety and efficacy for treating eye infections in children, covering dosing, clinical data, side‑effects, and alternatives.
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