Tag: narcolepsy with cataplexy
Narcolepsy with Cataplexy: How It’s Diagnosed and Why Sodium Oxybate Is the Gold Standard Treatment
Jan 23, 2026 / 8 Comments
Narcolepsy with cataplexy is a rare neurological disorder causing sudden muscle weakness triggered by emotion. Diagnosis requires sleep studies and CSF testing. Sodium oxybate (Xyrem/Xywav) is the only treatment proven to reduce both cataplexy and daytime sleepiness - but cost and dosing challenges limit access.
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